荧光底物BOC-Leu-Gly-Arg-氨基荧光素 货号13001-AAT Bioquest荧光染料

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品,欢迎访问AAT Bioquest荧光染料官网了解更多信息。

荧光底物BOC-Leu-Gly-Arg-氨基荧光素

荧光底物BOC-Leu-Gly-Arg-氨基荧光素

荧光底物BOC-Leu-Gly-Arg-氨基荧光素    货号13001 货号 13001 存储条件 在零下15度以下保存, 避免光照
规格 1 mg 价格 6564
Ex (nm) Em (nm)
分子量 819.87 溶剂 DMSO
产品详细介绍

简要概述

产品基本信息

货号:13001

产品名称:荧光底物BOC-Leu-Gly-Arg-氨基荧光素

规格:1mg

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:819.87

溶剂:DMSO

激发波长(nm):N/A

发射波长(nm):560

 

产品介绍

        荧光底物BOC-Leu-Gly-Arg-氨基荧光素是美国AAT Bioquest生产的荧光染料,这种基于氨基荧光素的探针是补体成分C3 / C5转化酶,凝血因子Xa和大豆胰蛋白酶样酶的发光底物。 它也被来自人类红细胞的高分子量巯基蛋白酶macropain水解。 可以使用我们的萤光素酶测定试剂盒检测蛋白酶释放的D-氨基荧光素。BOC-Leu-Gly-Arg-Aminoluciferin比广泛使用的荧光AMC底物Boc-Leu-Gly-Arg-AMC敏感得多。金畔生物是AAT Bioquest的中国代理商,为您提供最优质的荧光底物BOC-Leu-Gly-Arg-氨基荧光素。 

 

参考文献

Endotoxin assay by bioluminescence using mutant firefly luciferase
Authors: Kenichi Noda, Hitoshi Goto, Yuji Murakami, Abo Bakr F Ahmed, Akio Kuroda
Journal: Analytical biochemistry (2010): 152–155

 

相关产品

产品名称 货号
荧光底物Benzoyl-Leu-Gly-Arg-氨基荧光素 Cat#13000

说明书
荧光底物BOC-Leu-Gly-Arg-氨基荧光素.pdf

磷酸二铵Dap Boc标记 CAS 162558-25-0 货号5110-AAT Bioquest荧光染料

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品,欢迎访问AAT Bioquest荧光染料官网了解更多信息。

磷酸二铵Dap Boc标记 CAS 162558-25-0

磷酸二铵Dap Boc标记 CAS 162558-25-0

磷酸二铵Dap Boc标记 CAS 162558-25-0    货号5110 货号 5110 存储条件 在零下15度以下保存
规格 10 g 价格 3924
Ex (nm) Em (nm)
分子量 426.46 溶剂 DMF
产品详细介绍

简要概述

产品基本信息

货号:5110

产品名称:磷酸二铵Dap Boc标记

CAS:162558-25-0

规格:10g

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:426.46

溶剂:DMF

激发波长(nm):N/A

发射波长(nm):N/A

 

产品介绍

FMOC-Dap(Boc)-OH是一种常见的肽构建摸块。作为赖氨酸残基,其3氨基集团通常用于携带标签的部分如荧光染料、淬灭试剂或者生物素。金畔生物是AAT Bioquest的中国代理商,为您提供最优质的磷酸二铵Dap Boc标记。 

 

参考文献

Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks
Authors: Cadicamo CD, Asante V, Abu Ammar M, Borelli C, Korting HC, Koksch B.
Journal: J Pept Sci (2009): 272

[Drug (statine)-induced hepatitis]
Authors: Lazebnik LB, Zvenigorodskaia LA, Khomeriki SG, Efremov LI, Cherkashova EA.
Journal: Eksp Klin Gastroenterol (2009): 110

A simple microscale method for determining the relative stereochemistry of statine units
Authors: Preciado A, Williams PG.
Journal: J Org Chem (2008): 9228

Atovaquone-statine “double-drugs” with high antiplasmodial activity
Authors: Romeo S, Parapini S, Dell’Agli M, Vaiana N, Magrone P, Galli G, Sparatore A, Taramelli D, Bosisio E.
Journal: ChemMedChem (2008): 418

Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues
Authors: Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B.
Journal: Bioorg Med Chem (2008): 9471

Macrocyclic statine-based inhibitors of BACE-1
Authors: Barazza A, Gotz M, Cadamuro SA, Goettig P, Willem M, Steuber H, Kohler T, Jestel A, Reinemer P, Renner C, Bode W, Moroder L.
Journal: Chembiochem (2007): 2078

Stereocontrolled synthesis of 2,4-diamino-3-hydroxyacids starting from diketopiperazines: a new route for the preparation of statine analogues
Authors: Farran D, Toupet L, Martinez J, Dewynter G.
Journal: Org Lett (2007): 4833

A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis
Authors: Bridges KG, Chopra R, Lin L, Svenson K, Tam A, Jin G, Cowling R, Lovering F, Akopian TN, DiBlasio-Smith E, Annis-Freeman B, Marvell TH, LaVallie ER, Zollner RS, Bard J, Somers WS, Stahl ML, Kriz RW.
Journal: Peptides (2006): 1877

Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with beta-secretase
Authors: Zuo Z, Luo X, Zhu W, Shen J, Shen X, Jiang H, Chen K.
Journal: Bioorg Med Chem (2005): 2121

Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs
Authors: Johansson PO, Chen Y, Belfrage AK, Blackman MJ, Kvarnstrom I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B.
Journal: J Med Chem (2004): 3353

说明书
磷酸二铵Dap Boc标记 CAS 162558-25-0.pdf

蛋白酶荧光底物(BOC-VPR)2R110 货号13462-AAT Bioquest荧光染料

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品,欢迎访问AAT Bioquest荧光染料官网了解更多信息。

蛋白酶荧光底物(BOC-VPR)2R110

蛋白酶荧光底物(BOC-VPR)2R110

蛋白酶荧光底物(BOC-VPR)2R110    货号13462 货号 13462 存储条件 在零下15度以下保存, 避免光照
规格 1 mg 价格 1272
Ex (nm) 500 Em (nm) 522
分子量 1463.48 溶剂 DMSO
产品详细介绍

简要概述

产品基本信息

货号:13462

产品名称:蛋白酶荧光底物(BOC-VPR)2R110

规格:1mg

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:1463.48

溶剂:DMSO

激发波长(nm):498

发射波长(nm):520

 

产品介绍

蛋白酶荧光底物(BOC-VPR)2R110是美国AAT Bioquest生产的荧光底物,(BOC-VPR)2R110是α-凝血酶的敏感荧光底物。非荧光底物会产生亮绿色的荧光R110产品,该产品的发射光谱可以通过FITC滤光片组轻松检测到。该底物也已用于快速检测MRSA(耐甲氧西林的金黄色葡萄球菌)。金畔生物是AAT Bioquest的中国代理商,为您提供最优质的蛋白酶荧光底物(BOC-VPR)2R110。 

点击查看光谱

 

参考文献

Diabetogenic agent alloxan is a proteasome inhibitor
Authors: Wenjuan Zhou, Lingling Wei, Ting Xiao, Chunyou Lai, Min Peng, Lingli Xu, Xiangwei Luo, Shaoping Deng, Fengxue Zhang
Journal: Biochemical and Biophysical Research Communications (2017): 400–406

Delineation of molecular pathways involved in cardiomyopathies caused by troponin T mutations
Authors: Jennifer E Gilda, Xianyin Lai, Frank A Witzmann, Aldrin V Gomes
Journal: Molecular & Cellular Proteomics (2016): 1962–1981

Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts
Authors: Rajeshwary Ghosh, Sumanta K Goswami, Luis Felipe BB Feitoza, Bruce Hammock, Aldrin V Gomes
Journal: International Journal of Cardiology (2016): 923–935

Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1
Authors: Stefanie Grimm, Christiane Ott, Melanie Hörlacher, Daniela Weber, Annika Höhn, Tilman Grune
Journal: Biochemical Journal (2012): 127–139

说明书
蛋白酶荧光底物(BOC-VPR)2R110.pdf

BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3 货号5310-AAT Bioquest荧光染料

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品,欢迎访问AAT Bioquest荧光染料官网了解更多信息。

BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3

BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3

BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3    货号5310 货号 5310 存储条件 在零下15度以下保存, 避免光照
规格 1 mg 价格 1272
Ex (nm) Em (nm)
分子量 263.27 溶剂 DMF
产品详细介绍

简要概述

产品基本信息

货号:5310

产品名称:BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK]

CAS:187389-53-3

规格:1mg

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:263.27

溶剂:DMF

激发波长(nm):N/A

发射波长(nm):N/A

 

产品介绍

FMK肽是有效的,可透过细胞的,不可逆的capase抑制剂。它可用于检测和监测体外和体内应用中的细胞凋亡。BOC-ASP(OMe)-FMK是开发和制备基于FMK的capase抑制剂和探针的关键中间体。基于Asp(OMe)-FMK的半胱天冬酶抑制剂是细胞可渗透的并且不可逆地结合活化的半胱天冬酶以阻断细胞凋亡。作为分子链锯的胱天蛋白酶是细胞凋亡反应的核心组成部分。半胱天冬酶是半胱氨酸蛋白酶,其天冬氨酸残基在其底物中裂解。14种已知的哺乳动物半胱天冬酶中至少有7种在细胞凋亡中起重要作用。金畔生物是AAT Bioquest的中国代理商,为您提供最优质的BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK]。

 

参考文献

A glycine-leucine-rich peptide structurally related to the plasticins from skin secretions of the frog Leptodactylus laticeps (Leptodactylidae)
Authors: Conlon JM, Abdel-Wahab YH, Flatt PR, Leprince J, Vaudry H, Jouenne T, Condamine E.
Journal: Peptides (2009): 888

Design of nontoxic analogues of cathelicidin-derived bovine antimicrobial peptide BMAP-27: the role of leucine as well as phenylalanine zipper sequences in determining its toxicity
Authors: Ahmad A, Azmi S, Srivastava RM, Srivastava S, Pandey BK, Saxena R, Bajpai VK, Ghosh JK.
Journal: Biochemistry (2009): 10905

Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway
Authors: Warotayanont R, Frenkel B, Snead ML, Zhou Y.
Journal: Biochem Biophys Res Commun (2009): 558

Leucine-rich amelogenin peptide induces osteogenesis in mouse embryonic stem cells
Authors: Warotayanont R, Zhu D, Snead ML, Zhou Y.
Journal: Biochem Biophys Res Commun (2008): 1

Leucine-rich glioma inactivated 3 is involved in amyloid beta peptide uptake by astrocytes and endocytosis itself
Authors: Okabayashi S, Kimura N.
Journal: Neuroreport (2008): 1175

Leucine 7-proline 7 polymorphism in the signal peptide of neuropeptide Y is not a risk factor for exudative age-related macular degeneration
Authors: Kaarniranta K, Holopainen JM, Karvonen MK, Koulu M, Kallio J, Pesonen U, Terasvirta M, Uusitalo H, Immonen I.
Journal: Acta Ophthalmol Scand (2007): 188

Peptide-phospholipid cross-linking reactions: identification of leucine enkephalin-alka(e)nal-glycerophosphatidylcholine adducts by tandem mass spectrometry
Authors: Reis A, Domingues P, Ferrer-Correia AJ, Domingues MR.
Journal: J Am Soc Mass Spectrom (2006): 657

131I-Labeled arginine-arginine-leucine (RRL)-containing cyclic peptide (YCGGRRLGGC) for imaging prostate carcinoma
Authors: Shan L
Journal: (2004)

Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesis
Authors: Boabaid F, Gibson CW, Kuehl MA, Berry JE, Snead ML, Nociti FH, Jr., Katchburian E, Somerman MJ.
Journal: J Periodontol (2004): 1126

Cloning the tomato curl3 gene highlights the putative dual role of the leucine-rich repeat receptor kinase tBRI1/SR160 in plant steroid hormone and peptide hormone signaling
Authors: Montoya T, Nomura T, Farrar K, Kaneta T, Yokota T, Bishop GJ.
Journal: Plant Cell (2002): 3163

说明书
BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3.pdf